ABSTRACT
Background: The international, multi-center Pancreatic Cancer Early Detection (PRECEDE) Consortium enrolls high-risk individuals (HRIs) undergoing pancreatic ductal adenocarcinoma (PDAC) surveillance. Enrollment began in 2020, and despite challenges related to the COVID-19 pandemic, the PRECEDE Consortium rapidly accrued a large cohort of HRIs. The purpose of this study is to describe the characteristics of this cohort and assess racial, ethnic, and sex-based disparities. Method(s): The PRECEDE Consortium (NCT04970056) is a prospective, multicenter study focused on improving survival from PDAC through early detection. Data from all HRIs who met criteria for PDAC surveillance and enrolled between May 2020 - March 2022 were collected and included in the analysis. Result(s): During the study period, 1299 HRIs enrolled in PRECEDE at 32 centers. HRIs were excluded if enrollment data was incomplete or criteria for PDAC surveillance were not met. Of 1113 who were included, 47.2% met criteria for familial pancreatic cancer (FPC) and 45.4% had a family history of PDAC along with a PV in a PDAC-risk gene (BRCA1, BRCA2, PALB2, ATM, MLH1, MSH2, MSH6, PMS2, or EPCAM). The remainder had familial atypical mole melanoma syndrome (5.7%), Peutz- Jeghers syndrome (1.6%), or hereditary pancreatitis (0.2%). More females than males enrolled (65.9% vs. 33.5%). The distribution of HRIs by race and ethnicity is depicted;the majority identified as white (87.7%). Study participants were primarily from the US (82.7%), the median age was 61 (27-85) and 18.5% had Ashkenazi Jewish ancestry. Nearly all HRIs consented to allow access to imaging data (99.6%), collection of germline DNA (97.7%), and biosample collection (99.5%). There were no race, ethnicity, or sex-based differences in rates of consent for collection of imaging, DNA, or biosamples. Conclusion(s): Enrollment of HRIs in prospective studies of PDAC surveillance is essential for advancing early detection research in PDAC. A distinct advantage of the PRECEDE Consortium for examining enrollment disparities is that recruitment began in 2020, providing a unique and current snapshot of the international PDAC surveillance landscape. Despite the recent attention on addressing disparities in healthcare delivery, significant racial, ethnic, and sex-based disparities persisted in the cohort of HRIs enrolled in the PRECEDE Consortium. Ensuring that the diversity of participants in the PRECEDE Consortium mirrors the communities served by participating centers is crucial. Further examining and addressing the reasons for these disparities is a major focus of the PRECEDE Consortium moving forward.
ABSTRACT
Change is the only constant, they say;with technology, the changes seem to be happening ever so often. The question that arises is to what extent have the changes been implemented and what are the capabilities of systems in various sectors to implement these changes. COVID-19 is a medical catastrophe, but it has come with a silver lining. It has forced everyone to adapt to using technology. People in different sectors were forced to ensure that they learnt the new ways of working. Work from home became the norm, which in turn led to the imperative nature of connectivity through the online platforms. Smart cities which were only in the planning and policy development stage suddenly saw a "jugaad" technology playing a role in it. This "jugaad" technology will work for the interim period and will most definitely initiate the start of complete connectedness between individuals and companies and in turn developing smart cities. In this chapter, the aim is to focus on understanding the barriers of use of technology in the education sector. There are many stakeholders which can be considered in the education sector. It is impossible to consider all dimensions in one study. Our aim is to determine the barriers faced by teacher trainers while training in the online mode. We use a multicriteria decision making tool DEMATEL to further establish the cause-andeffect group between the criteria. It is necessary to remove the antecedents of the consequents and establish a better education system and lead to smart education for smart cities. © 2023 Scrivener Publishing LLC. All rights reserved.
ABSTRACT
The response to the COVID-19 pandemic in the US has been heavily criticized for its reliance on people's voluntary uptake of health protective behaviors like mask-wearing. Such voluntary approaches to public health crises assume individuals are altruistic and will put the good of the community before themselves. However, social groups operate in distinct ways and have different motivations. Since ideas of individualism in the US are both gendered and racialized, we adopt an intersectional approach to examine how both race and gender interact to shape mask-wearing behaviors. Using a survey of 1,269 adults in the US, we find that white women are less likely to wear a mask than Latinas and Black women but observe no differences amongst men. Our data suggest that these differences arise because white women are more likely to approach mask-wearing as a personal choice, whereas Latinas and Black women are more likely to take a collectivist approach and view mask-wearing as a social responsibility. We highlight the importance of adopting an intersectional approach to understand true variability in health protective behaviors. We also draw attention to the importance of developing community-specific public health messaging that resonates with its members' norms and experiences. © The Southern Sociological Society 2022.
ABSTRACT
SESSION TITLE: Novel Education and Assessments of Trainees SESSION TYPE: Rapid Fire Original Inv PRESENTED ON: 10/17/2022 12:15 pm - 1:15 pm PURPOSE: Utilization of Virtual Escape Rooms (VER) in medical educational has been shown to improve learner satisfaction and reinforce knowledge in the field of pulmonary and critical care medicine.1-6 Data lacks in effectiveness of VER for knowledge acquisition. This study aimed to evaluate perception of VER and effectiveness in gain of knowledge amongst pulmonary and critical care fellows. METHODS: This prospective study was conducted following the 2022 CHEST Pulmonary and Critical Care Fellow’s Virtual course. The course was deployed using Zoom© meeting platform. The two-day back-to-back course was structured as five, 50-minute virtual sessions and a VER session at the end of day two. The VER has been previously validated in two recent national scientific meetings and assesses high-yield pulmonary and critical care medicine topics. A pre- and post- course assessment with 9 clinical knowledge questions (one for each of the five virtual session and 4 for the VER session). A total score was obtained from each category as well as a total summative score. Additionally, audience perceptions of VER were surveyed with pre-and post-course assessment using a 5-point Likert Scale (1=strongly disagree and 5 = strongly agree) and an average for each question calculated. RESULTS: Of 247 trainees, 59 and 29 participants completed the pre- and post-course test (20 completed both tests). The clinical knowledge assessment total score, virtual sessions, and escape room categories scores, were significantly higher in the post- than the pre-course test. There was a positive perception of participants towards VER as an engaging experience and as an activity that augments learning. Participants were supportive of similar interactive VER activities at future events. CONCLUSIONS: The implementation of an educational virtual escape room (VER) at a national pulmonary and critical care fellows’ virtual course successfully increased knowledge acquisition among participants while providing an enriched learning experience. CLINICAL IMPLICATIONS: The deployment of VER offers medical educators with another tool for virtual education. To our knowledge, this is the first time a VER has been deployed and studied amongst pulmonary and critical care fellows. We consider this generation of physicians highly exposed and well-versed in virtual educational offerings, likely directly related to the COVID-19 pandemic. Apart from its educational value, the VER format exposed trainees to a collaborative educational experience.7 DISCLOSURES: No relevant relationships by Mauricio Danckers No relevant relationships by Michele Iguina No relevant relationships by Viren Kaul No relevant relationships by William Kelly